[post_page_title]Sara Gilbert as Leslie Winkle[/post_page_title]
Leslie works alongside Leonard at Caltech as she, too, works in the field of experimental physics. The character is written as basically the female version of Leonard, who wears the same clothes and glasses frames.
Though (the real) Leonard plucks up the courage to ask Leslie out on a date during the first season, it’s Howard that Leslie eventually ends up having a relationship with, even though she doesn’t reciprocate his feelings. Additionally, Leslie is known to have an everlasting feud with Sheldon throughout the series.
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